Chemogenetic dissection of the primate prefronto-subcortical pathways for working memory and decision-making
نویسندگان
چکیده
منابع مشابه
The primate working memory networks
Working memory is the term commonly used for the ability to maintain information in memory over a time span of a few seconds. Working memory constitutes a core component of higher cognitive functions including language, problem solving, and reasoning (Baddeley, 1992). Lesion studies first localized working memory functions in the cortical surface of the frontal lobe (Jacobsen, 1936; Milner, 196...
متن کاملThe primate working memory networks.
Working memory has long been associated with the prefrontal cortex, since damage to this brain area can critically impair the ability to maintain and update mnemonic information. Anatomical and physiological evidence suggests, however, that the prefrontal cortex is part of a broader network of interconnected brain areas involved in working memory. These include the parietal and temporal associa...
متن کاملDynamic Decision-Making 1 Running Head: WORKING MEMORY AND DYNAMIC DECISION MAKING Working-Memory Load and Temporal Myopia in Dynamic Decision-Making
We examined the role of working-memory (WM) in dynamic decision-making by having participants perform decision-making tasks under single-task or dual-task conditions. In two experiments participants performed dynamic decision-making tasks where they chose one of two options on each trial. The Decreasing option always gave a larger immediate reward, but caused future rewards for both options to ...
متن کاملWorking-memory load and temporal myopia in dynamic decision making.
We examined the role of working memory (WM) in dynamic decision making by having participants perform decision-making tasks under single-task or dual-task conditions. In 2 experiments participants performed dynamic decision-making tasks in which they chose 1 of 2 options on each trial. The decreasing option always gave a larger immediate reward but caused future rewards for both options to decr...
متن کاملWorking Memory and Decision-Making in a Frontoparietal Circuit Model.
Working memory (WM) and decision-making (DM) are fundamental cognitive functions involving a distributed interacting network of brain areas, with the posterior parietal cortex (PPC) and prefrontal cortex (PFC) at the core. However, the shared and distinct roles of these areas and the nature of their coordination in cognitive function remain poorly understood. Biophysically based computational m...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Science Advances
سال: 2021
ISSN: 2375-2548
DOI: 10.1126/sciadv.abg4246